SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33992c95f51ffdb39fc78bb6581749036a25244136ef250c50451ebc8c6cf20' 
  AND token = 'InP0FE0iriXh5N2chQt34/mL3sssZBm+fnrD0dPs0Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}