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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c11867e4960d8c0ac2c101923bef1982be69ba0f68017701a893282be3776f' 
  AND token = 'V/Zv+OX7c89FOhLBan3+YYhPw9Z2bf2mC58Argg05vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}