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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a6a7767122c9298a7f775c6f79e1fece564c554bb3b07e1d6aa025f557319e3' 
  AND token = 'ilkewx9nafZw3QMov9gGKZvD0kZSQJd5R1eDDfiYJw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}