SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fbc7d1abfea395d744433086c9c22c4a52854da5b1f727a669108a1a2a4fee4' 
  AND token = 'd/dnVPEqpEuD1AYx4vQA+KGog2EE7/bY+w4wX54ZFro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}