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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95299d57295a6bf38df8f2639ee4d4d1865802feb9aee1f4fec2439150cbab01' 
  AND token = '4TxLwJkUpBbhU3AkF3IOu3amWLffrIaw7ZLUpQBtWw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}