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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '833a878be30baa34785250507a6e1b9c5fef4cac882e9b1e8b9c85a122b5374e' 
  AND token = 'DSmGgjyaVlEw6AiN+LmP9wMTctT4XRuxAmpEYCp185k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}