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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f81ee01643a8be2f3069cb723487d9eb6ac21456944db45e63ccf2902111bd7' 
  AND token = '6JqvBygu+okcpesUIGwBmq6cAWee1tHXr7Pxo0rb5Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}