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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8feabf75385d7073a6205426ee1b4aadcc61a020f93bd76e071fb4032d3b21' 
  AND token = 'xm8PHzGPD5dolTbqjyCdIgQaZG8AXb7Y4C4pF1hImDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}