SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5deedb5d6d7178374840d05e5474bdc7f41e0dba92c54155954845348c38481' 
  AND token = 'Ma0n7PBO48/MjAxaC4GJs8uwbiCLVath9cRHFa2uX7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}