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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b44303949e3bfd09cb8beb91a4bb9fba5664e7a817b4aa3f47b89267bc077e8' 
  AND token = 'VpdxXeMlPodUaMIU3w19N6Ox224DcJ3BwhCfrqqjFVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}