SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185a9ac2ebc5f7190cc2a74713ce95761f345099a86557e54a5115d4fa4daff2' 
  AND token = 'bNV+B394phewe0r4OKoMGOo/tsomUb97x8EExEXk9dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}