SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b7874e69e069a7715d1d899162e377d6f04f49a476ba05d87bc1b04cf25791' 
  AND token = 'Bra8dt4ZsgJuUfteyDODpBBw0KrQEb1X2BtoH3iCCMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}