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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946a18e93a792921891cbb0979d1e97390dfe116f9f08c08ec72d9c0d46038f7' 
  AND token = 'lRZO+lQZoP5U4GB5B/Lede1A2kkK6QEGx9U2xRcKD0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}