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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd41f4c89b7606fea692426a1c91ab89d9736363711cff55d71f8168d3c58fd' 
  AND token = '2agTjXNCJOWPbDEdUWu9WOkI1LN5O+9dSsLsHtYxcpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}