SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6cd5bfb54eaf844133eef4247d3e8deb90aff0f9fe4461424bef094f1789a6' 
  AND token = 'NFtsOZqdPUkkdMK1sAhyKhpGfO55wX8hYyUvSzHhbhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}