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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c8a249963e6f07679f0e0402b4ec36225a0de0d787385927b68b17e0810a4d' 
  AND token = 'xqhIxtwD4rCJPMW68XfHEUAqBdy1kc1YhGXyzlYwbh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}