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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a142042224160342bebb900f0129652ff22f37c981a12517e02932be64564302' 
  AND token = 'wK9et5RrBF4uQQorL2JX3J5+eU/4zpjfcLRj9IRtcDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}