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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b900d22ed1ec41602c717ede4b971b33969c2e11e8da720a656d92c4fd14fb80' 
  AND token = 'ibCYFkbbpj+n9Hb8yUnnh8SnZqgn/dd8+y8E38VlI/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}