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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bc6e3f08ef9e83eb023e83b5b9058573263f0add506c970c6b43c56f5220b8' 
  AND token = 'L0FUusvIUbGQsMxIfkHQYFyVN6o8EUCv9ZlVE87Md5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}