SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97ee88f5fdd7a9ba3620081a6e5d9ee2c2337f6b2bf37e215a0157a61c8ed411' 
  AND token = 'vwR2l9hk2UAX8TI7lUpzqFDX0fpLy2Q7unxq5nmWA/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}