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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf6fe68a9d56620ee3db0155a251de9349b496711ac3b32a93a74d53de5f2d8' 
  AND token = 'CBX4CXTFNCeE3e692LRX1xSbTsWduwY1Xq3OT85hXGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}