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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f8563a96ef803e87860253093824f97f112f3c1a9bf64328cc21968ad37adb8' 
  AND token = '7mQkkB9kjakrkynovmYWki2FiIgGs0IqnSpi5BkmrHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}