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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746bfc95eb8f70c4ce053de8131c8db57edd60dc0adbf93eee3ba1530f4e45cf' 
  AND token = 'KhTSCBPLZx/4q9HUuEK7OK9WgbT0GpzcHDPU2HEdu14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}