SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2471e2f2cb29cf0e09fb0679b4c12ccd5f055bc01a7574140c1b4d354ace8c' 
  AND token = 'OxiooyfnpTQPVtaWkKW8yEJUVJ0t5sYUNhhkv/a+r6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}