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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3971c4b42d5a4ceb4c0ac21c3966a2fdc9875ca6879ebe051a87c2e958e4f094' 
  AND token = 'SNFXAWgeJXKJguYE8Y011T4dRAe8Mz6izHGhdqzMzDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}