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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5c99a6466c092a7c135a87ba7a3e150f545e2f50020a2966b43fb84dbc2277e' 
  AND token = '/Ov0+xdnC3SgY+Cuv/epcbDwCYAfwqpbn2WZ7Fii9bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}