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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724477ec27415523e9b3eff42cb593e090fad969a834fd9a9f37c3c9aaacc0f5' 
  AND token = 'XUeiJn5n9zJ+t2pGkCPJwUHqNIC0QU7jQayi8ydnUkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}