SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01849253577bd4e4e72a778a97f42ab1dd55dfdd1949a4006f0d7b06b7c58fa8' 
  AND token = 'iXeC2wyGSk/+3dXfENUq2F9yHh1x7XWJ2B6HsXRk9/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}