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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b4c5c0087bfeefd66c473487c322efc70fee7f14664ee82d337dd0d00e4b58' 
  AND token = 'qaaBR0TGQ48wVBEn/qByqAM1lFyXUk6f4Y4DOirRx0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}