SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '130d9f21660da049741b26dd9d25e35d1c7f604561b4b788d79b5a3c09b02d90' 
  AND token = 'VEkERbQV3OcvZk2i4o/aS9TCi9fO/WCeG9VUzUCNOrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}