SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46e0960c2b6fa23bc88f15d27525599252067157933313d06d41954cef92ed2' 
  AND token = '3gapvxhbVTZ5iWBaoZNc78FwZys7JBA9i9ZwHbUuqps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}