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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9ae9868eab6c060c1bf5a1573e6fe3865bf868c4c72b4ad24e1ca3329afed1' 
  AND token = 'mmbxcuHJVJpS/qvRF7sMiCrb+bOd009xxLQCHuJmmVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}