SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b429f454dcbd43f92299df04e89c7ab152048dba800d6f054623d440d2491302' 
  AND token = 'gWqTYflonq/AkA6/zeN6gj1GLoc3nlogjFFXVijsm4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}