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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2595d83acf0d4ed4010ea29e3e38cc5bb4713f60fb424d45eec29d97309d72af' 
  AND token = 'aveoynVZm0UOTDwDB6kLy9nxUJuleHbhu5Op6Qd2vzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}