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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc0e9b470ab776fff8e6f486384548ae109d93b1ff3efedff11b08d96cb4c49' 
  AND token = 'faQ2kaA1q5ZDX3KdkIs/4qA4yjWs3iTLWZdWUGAhM3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}