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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa5530e8d2c7e2789873dff8f35e3323f1d922ff6ec918c56a24431e0124c2e' 
  AND token = 'W4Oznez9XBHiZyMBVNwWYeKYx7diUAi3XxSu9774uqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}