SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa05ea45b23adb35db4f0a57e3964c936a990d45037921fe31848be716a51f0' 
  AND token = 'nxK6H1BoBHVz453tWFSjzmxqEyxJ8jXF6Ykl2/LbQs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}