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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f5ada4d37d3833828983fc655b7f7ff2dd7a68affcbd11e2371f21ac1659d0' 
  AND token = 'wBbEP8Gw2apZuzbX7HkGbiI4IPKSFDGxqGVcDUc1iHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}