SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12189f01e264fa1eaa75ea593a4ec5241c08794f21befdaeb7ae14501e3893d8' 
  AND token = 'NUmN4fItjvpa5XjHdGqbJmCxxoZiVtYPoEib5+GhhCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}