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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53e0a3901b4bf94192f2d7991b1091f617c7f86ada768e604ecc80503fba224' 
  AND token = 'fnesJzUhNATP0vhx9u1hQWd8Gl/Q0JWSRdOp6CG183s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}