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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605f65951252ac5e6a6204d50c43389928172d277902ec034c8ba762c995113a' 
  AND token = '8R9xKTc2xCFIX7twa8L91+ACunEeZWCVXcPQCqCTpwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}