SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad98247dbf7cc32f77f2faaa06f12d7fe6bba0578c739a6d456a165e27c6c193' 
  AND token = 'Djfahui5Tg7V1zmxpIFFmEaQhN58aqE+YL67oqX20Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}