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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc1d4285d16e113ca84fdb078ebd6d5afc2add2e6552cbfd9c2539c0924eac5' 
  AND token = 'tTcXuFR1FXpupjdAGLi8pv08mJsQ85VBjjAKSOtmlOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}