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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d9c3265be7a266503565d39f6da56b05c0bb971cbe09301b3d31ebac15fce60' 
  AND token = 'F9HYAcOXxl8aKNJZWNsF9KYcUCGIFFM/H1sBUyrHMzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}