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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23000b2b4fa982576abb4a9c814ac9bc334c9215a9295e9e40c93c5727a08b26' 
  AND token = '2HDI2IZPckyQDL0UM39Q4AAJ+JwoaFIEDwL+D5VQSYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}