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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b26cdbd0243d561af98656572af24a3fdf84fdb26345fea651dffc8b19ee95a9' 
  AND token = 'uHoTnmEbB35O0BS4CBXay7qN31BgnPxznIDYbvkH6Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}