SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35e9022a923c30bb53b634e211dc300b5d1bb4aa314e7dba630cbbc7b996db6' 
  AND token = 'D/o3XAtABxutXEg31KTxrJqMw76GdFtR2PQ7f1H2KW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}