SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44db3e87ada2236501cb2307d8d2c3970a244b2cfe7631220cfcb96c04da9432' 
  AND token = 'U4KbG/7iX0RsTkvSfNf6cber1hO6CK553kMGtueHSCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}