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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c824051fe1f295f493ce792bce1e79247aa24f5a2508ca8d2b1a551a0f4e32' 
  AND token = 'QlVH6y5YjdjlHD+tMwkgrTQ7TmbxsH90OCVvnkCwLQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}