SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df57a5b8c60a4bb7d47f448b803d26f2ca18379ac37328b1346c38c9672b1407' 
  AND token = 'fOqpkwBGjfv9JLRInMkhWDypU2k3O0ZNV/Tz0Zr4g7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}